Which side effect is commonly associated with tricyclic antidepressants?

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Xerostomia, or dry mouth, is a commonly associated side effect of tricyclic antidepressants (TCAs). This occurs because TCAs have anticholinergic properties, which block the action of acetylcholine at muscarinic receptors. Reduced stimulation of the salivary glands leads to decreased saliva production, resulting in dry mouth.

This side effect can significantly impact a person's oral health, leading to difficulties in speaking, eating, and an increased risk for dental caries due to lower saliva availability that typically helps protect the teeth. It is essential for healthcare providers to inform patients about the possibility of xerostomia and to suggest strategies for management, such as staying hydrated, using saliva substitutes, or obtaining regular dental check-ups.

While weight loss, euphoria, and bradycardia can occur in various contexts, they are generally not the primary concerns associated with TCAs. Weight gain is often more prevalent with these medications due to their effects on metabolism and appetite. Euphoria is not a typical side effect; in fact, TCAs generally aim at mood stabilization rather than eliciting euphoric responses. Bradycardia may be seen as a side effect due to some TCAs' effects on heart rate, but xerostomia

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