Which of the following is an antifungal ointment taken orally?

Fluconazole is an antifungal medication that is typically available in oral form and is effective against a variety of fungal infections. It works by inhibiting the synthesis of ergosterol, which is a critical component of fungal cell membranes. This action disrupts the cell membrane function, leading to the death of the fungal cells. Fluconazole is commonly used to treat systemic fungal infections and yeast infections, making it a widely used oral antifungal option.

While both Nystatin and Ketoconazole can also be used for treating fungal infections, Nystatin is primarily available as a topical treatment and is usually not taken orally for systemic infections, but rather for localized infections such as oral thrush. Ketoconazole, on the other hand, is available in both topical and oral formulations but has fallen out of favor for systemic use due to safety concerns regarding liver toxicity. Therefore, when considering an antifungal ointment specifically indicated for oral administration, Fluconazole is the most appropriate choice.