Which medication is effective against bacterial infections by weakening the bacterial cell wall?

Prepare for your StudentRDH Pharmacology Exam. Review flashcards and multiple-choice questions with hints and explanations. Get exam-ready!

The medication that effectively weakens the bacterial cell wall is indeed cephalosporin. This class of antibiotics works by inhibiting the synthesis of peptidoglycan, an essential component of bacterial cell walls. As the cell wall becomes compromised, bacteria become unable to maintain their shape and integrity, ultimately leading to cell lysis and death, especially in actively dividing organisms.

While penicillin also targets the bacterial cell wall by similar mechanisms, cephalosporins are a subclass of beta-lactam antibiotics that have a broader spectrum of activity against various bacterial strains. They can be classified into generations, each with varying effectiveness against different groups of bacteria, which is important in treating specific infections.

Tetracycline and ciprofloxacin, on the other hand, do not target the bacterial cell wall. Tetracycline inhibits protein synthesis by binding to the 30S ribosomal subunit, and ciprofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, thus interfering with DNA replication.

In summary, cephalosporins achieve their antibiotic effect through the destruction of the bacterial cell wall, leading to cell death, making this method a crucial mechanism of action in the management of bacterial infections.

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