Which four pharmacokinetic properties determine the speed of onset, intensity of effect, and duration of a drug's action?

The correct response identifies the four key pharmacokinetic properties: absorption, distribution, metabolism, and elimination.

Absorption refers to the process by which a drug enters the bloodstream from its site of administration. This process can significantly influence how quickly a drug takes effect; for example, intravenous injections lead to rapid onset due to direct entry into circulation, whereas oral medications may take longer as they must first pass through the gastrointestinal tract.

Distribution is the dispersion of the drug throughout the body's fluids and tissues. Factors such as blood flow, tissue permeability, and protein binding influence how effectively and quickly a drug reaches its target site.

Metabolism involves the biochemical modification of the drug, often occurring in the liver. This process can activate or inactivate a drug, affecting both the intensity and duration of its effects. The rate of metabolism varies between drugs and individuals, influenced by factors such as genetics and the presence of other substances.

Elimination is the process through which the drug exits the body, primarily via the kidneys but also through bile, sweat, and other routes. The elimination half-life of a drug can greatly affect how long its effects are felt and how frequently it needs to be administered.

In summary, these four properties – absorption, distribution, metabolism, and elimination