What is the recommended premedication dosage for a pediatric patient who can take oral medication with no hypersensitivity to penicillin?

The correct choice is based on established guidelines for antibiotic prophylaxis in pediatric patients who do not have hypersensitivity to penicillin and are able to take oral medication. The recommended dosage of oral amoxicillin for premedication in children undergoing dental procedures is typically 50 mg/kg, up to a maximum of 2,000 mg in total. This recommendation is in place to effectively reduce the risk of infective endocarditis during dental treatment.

The rationale behind using amoxicillin specifically applies to its effectiveness against common bacteria found in the oral cavity. Administering the correct dosage within one hour prior to the procedure ensures optimal levels of the antibiotic are present in the bloodstream during the procedure when bacteremia could occur, thus providing sufficient protection.

In contrast, the other dosages presented exceed the recommended limit or present inaccuracies:

• A dosage of 2 g/kg is incorrect as it vastly exceeds the standard guideline, which caps at 50 mg/kg.

• A dosage of 500 g/kg is not clinically viable; it would be a dangerously high and unrealistic amount.

• Clindamycin is an alternative for those allergic to penicillin, but the correct dosage for clindamycin is 20 mg/kg, not 60 mg/kg.

Therefore