What is the characteristic of topical/transdermal drug administration?

Topical and transdermal drug administration is characterized by slow absorption, which is a key aspect of its pharmacokinetics. This method is designed to provide a gradual release of the drug into the bloodstream through the skin, allowing for a steady pharmacological effect over an extended period.

In transdermal applications, the drug is formulated into patches or other delivery systems specifically designed to penetrate the skin barrier slowly. This slow absorption helps maintain therapeutic drug levels over time while minimizing peak plasma concentrations, which can reduce the risk of side effects.

While some factors can influence the absorption rate, such as the drug's formulation, the condition of the skin, and the surface area of application, the fundamental characteristic of transdermal administration remains its propensity for slow absorption. This contrasts with other routes of administration, like intravenous injections, which lead to rapid absorption and immediate effects.