What is a common side effect of antidepressants?

Xerostomia, or dry mouth, is a common side effect associated with many classes of antidepressants, particularly tricyclic antidepressants (TCAs) and some selective serotonin reuptake inhibitors (SSRIs). This occurs because these medications can inhibit the secretion of saliva, leading to a reduced flow of saliva in the mouth. Patients experiencing xerostomia may find it uncomfortable, and it can contribute to oral health issues such as increased risk of dental caries and oral infections.

While antidepressants can indeed lead to a variety of side effects, including nausea, insomnia, and changes in appetite (which can relate to eating disorders like bulimia), xerostomia stands out as a specific and notable consequence related to the mechanism of action of these medications. Understanding the side effects helps dental professionals manage these conditions in patients who are taking antidepressants, ensuring they receive appropriate care for oral health alongside their mental health treatment.