What class of drugs is primarily used as anti-GERD and anti-ulcer agents?

The primary class of drugs used specifically as anti-GERD (Gastroesophageal Reflux Disease) and anti-ulcer agents includes proton pump inhibitors (PPIs) and H2-receptor antagonists. These agents work by reducing stomach acid production, which helps in the healing of ulcers and alleviating the symptoms associated with GERD. The mechanism of action makes these drugs particularly effective for managing conditions related to excessive stomach acid.

While anti-histamine agents can influence stomach acid to some extent through H2-receptor antagonism, they are not the first line for GERD or ulcers as combined therapies like PPIs offer a more comprehensive approach. Anti-fungal agents are focused on treating fungal infections and have no direct effect on gastric acid or ulceration. Similarly, anti-inflammatory agents are aimed at reducing inflammation and do not target the underlying acidic environment in the gastrointestinal tract related to GERD or ulcers. Thus, the most appropriate categorization of drugs addressing these specific gastrointestinal conditions is indeed those classified directly as anti-GERD and anti-ulcer agents.