What can Pilocarpine overdose cause?

Pilocarpine is a cholinergic agonist that stimulates muscarinic receptors, leading to various physiological effects. When there is an overdose of Pilocarpine, it can significantly enhance the activities of the exocrine glands, resulting in increased secretion from these glands.

Increased salivation occurs as Pilocarpine stimulates the salivary glands, which leads to an abundance of saliva in the mouth. This effect is often utilized therapeutically in conditions like xerostomia (dry mouth).

Increased lacrimation, or tear production, is also a result of Pilocarpine's action on the lacrimal glands. This effect helps in relieving dry eye symptoms as it promotes moisture in the eyes.

Increased urination can happen because stimulation of muscarinic receptors in the bladder can enhance bladder contractions, leading to more frequent urination.

The combination of these effects illustrates the cholinergic properties of Pilocarpine and the impact of an overdose, which can lead to systemic responses characterized by heightened secretion across various exocrine glands. This is why the option indicating all of the above outcomes is appropriate, as all are potential effects of Pilocarpine overdose.