Tetracyclines are contraindicated during pregnancy. Metronidazole is considered a safe alternative. Which statement is true?

Tetracyclines are indeed contraindicated during pregnancy due to their potential to cause permanent discoloration of teeth and affect bone development in the fetus. These antibiotics can cross the placenta and potentially lead to harmful effects on the developing baby. It is important for healthcare providers to avoid prescribing tetracyclines to pregnant women to prevent these adverse outcomes.

Metronidazole is considered safer for use in pregnancy, particularly after the first trimester, although healthcare providers typically weigh the risks and benefits before prescribing it. While there are some concerns regarding its use in the first trimester, it is generally preferred over tetracyclines due to its lesser risk of teratogenic effects.

As both statements are accurate regarding the contraindication of tetracyclines during pregnancy and the considered safety of metronidazole as an alternative, the correct conclusion is that both statements are true.